Reaction: Tiotropium to 2 products

Reaction
Tiotropium
DB01409
    Dithienylglycolic Acid
    DBMET02592
    N-methylscopine
    DBMET02593
    Reaction type
    hydrolysis
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    inactive
    References
    1. Price D, Sharma A, Cerasoli F: Biochemical properties, pharmacokinetics and pharmacological response of tiotropium in chronic obstructive pulmonary disease patients. Expert Opin Drug Metab Toxicol. 2009 Apr;5(4):417-24. doi: 10.1517/17425250902828337 . [Article]
    2. FDA Drug Approval Package: Tiotropium Bromide Powder for Inhalation [Link]
    3. FDA Approved Drug Products: Tiotropium and Olodaterol Metered Inhalation Spray [Link]
    4. FDA Approved Drug Products: Tiotropium Inhalation Spray [Link]
    5. FDA Approved Drug Products: Tiotropium Metered Inhalation Spray [Link]
    Comments
    Not Available
    Enzymes
    Not Available