Reaction: Oxybutynin to 1 product

Reaction
Oxybutynin
DB01062
N-desethyloxybutynin
DBMET00381
Reaction type
N-deethylation
Direction
Not Available
Major circulating metabolite?
No
Spontaneous?
No
Activity
active
References
  1. Douchamps J, Derenne F, Stockis A, Gangji D, Juvent M, Herchuelz A: The pharmacokinetics of oxybutynin in man. Eur J Clin Pharmacol. 1988;35(5):515-20. doi: 10.1007/bf00558247. [Article]
  2. Yarker YE, Goa KL, Fitton A: Oxybutynin. A review of its pharmacodynamic and pharmacokinetic properties, and its therapeutic use in detrusor instability. Drugs Aging. 1995 Mar;6(3):243-62. doi: 10.2165/00002512-199506030-00007. [Article]
  3. Ditropan XL FDA label [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableconfirmed