Reaction: Anastrozole to 1 product

Reaction
Anastrozole
DB01217
    3,5-Bis-(2-methylpropiononitrile)-benzoic acid
    DBMET02829
    Reaction type
    N-dealkylation
    Direction
    Not Available
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    inactive
    References
    1. Kamdem LK, Liu Y, Stearns V, Kadlubar SA, Ramirez J, Jeter S, Shahverdi K, Ward BA, Ogburn E, Ratain MJ, Flockhart DA, Desta Z: In vitro and in vivo oxidative metabolism and glucuronidation of anastrozole. Br J Clin Pharmacol. 2010 Dec;70(6):854-69. doi: 10.1111/j.1365-2125.2010.03791.x. [Article]
    Comments
    Not Available
    Enzymes
    Not Available