Reaction: Loxoprofen to 1 product

Reaction
Reaction type
reduction
Direction
Major circulating metabolite?
Yes
Spontaneous?
No
Activity
active
References
  1. Shrestha R, Cho PJ, Paudel S, Shrestha A, Kang MJ, Jeong TC, Lee ES, Lee S: Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation. Pharmaceutics. 2018 Aug 2;10(3). pii: pharmaceutics10030112. doi: 10.3390/pharmaceutics10030112. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Carbonyl reductase [NADPH] 1Not AvailableNot Availableimplied