Reaction: Testosterone to 1 product

Reaction
Testosterone
DB00624
Estradiol
DBMET00491
Reaction type
Not Available
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. [Article]
  2. Ishikawa T, Glidewell-Kenney C, Jameson JL: Aromatase-independent testosterone conversion into estrogenic steroids is inhibited by a 5 alpha-reductase inhibitor. J Steroid Biochem Mol Biol. 2006 Feb;98(2-3):133-8. doi: 10.1016/j.jsbmb.2005.09.004. Epub 2005 Dec 28. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 19A1Not AvailableNot Availableconfirmed