Reaction: SN-38 to 1 product
O-glucuronidationMetabolism of Sacituzumab govitecan
SN-38 is converted to 10-O-glucuronyl-SN-38 by UDP-glucuronosyltransferase 1A1.
- Direction
- Activity
- inactive
What you can answer from here — as of April 24, 2020
1EnzymeEach linked to its target cardListed above
Which other drugs are metabolised by UDP-glucuronosyltransferase 1A1, and which of those pairings are clinically significant?
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