Reaction: Apomorphine to 2 products

Reaction
Apomorphine
DB00714
Apocodeine
DBMET03128
Isoapocodeine
DBMET03129
Reaction type
O-methylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. van der Geest R, van Laar T, Kruger PP, Gubbens-Stibbe JM, Bodde HE, Roos RA, Danhof M: Pharmacokinetics, enantiomer interconversion, and metabolism of R-apomorphine in patients with idiopathic Parkinson's disease. Clin Neuropharmacol. 1998 May-Jun;21(3):159-68. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Catechol O-methyltransferaseNot AvailableNot Availableimplied