Reaction: 6,7-dichloro-3-hydroxy-1,5 dihydro-imidazo[2,1-b]quinazolin-2-one to 1 product

Major circulating metaboliteMetabolism of Anagrelide

6,7-dichloro-3-hydroxy-1,5 dihydro-imidazo[2,1-b]quinazolin-2-one is converted to 2-amino-5,6-dichloro-3,4,-dihydroquinazoline by Cytochrome P450 1A2.

Reaction
6,7-dichloro-3-hydroxy-1,5 dihydro-imidazo[2,1-b]quinazolin-2-one
DBMET00772
Direction

What you can answer from here — as of June 08, 2020

1EnzymeEach linked to its target card
Listed above

Which other drugs are metabolised by Cytochrome P450 1A2, and which of those pairings are clinically significant?

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