Reaction: Remimazolam to 1 product

Reaction
Remimazolam
DB12404
CNS7054
DBMET03182
Reaction type
hydrolysis
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
inactive
References
  1. Freyer N, Knospel F, Damm G, Greuel S, Schneider C, Seehofer D, Stohr T, Petersen KU, Zeilinger K: Metabolism of remimazolam in primary human hepatocytes during continuous long-term infusion in a 3-D bioreactor system. Drug Des Devel Ther. 2019 Apr 2;13:1033-1047. doi: 10.2147/DDDT.S186759. eCollection 2019. [Article]
  2. FDA Approved Drug Products: Byfavo (remimazolam) for intravenous injection [Link]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Liver carboxylesterase 1Not AvailableNot Availableconfirmed