Reaction: Opicapone to 1 product

Reaction
Opicapone
DB11632
    BIA 9-1103
    DBMET03236
    Reaction type
    sulfation
    Direction
    Major circulating metabolite?
    Yes
    Spontaneous?
    No
    Activity
    inactive
    References
    1. Almeida L, Rocha JF, Falcao A, Palma PN, Loureiro AI, Pinto R, Bonifacio MJ, Wright LC, Nunes T, Soares-da-Silva P: Pharmacokinetics, pharmacodynamics and tolerability of opicapone, a novel catechol-O-methyltransferase inhibitor, in healthy subjects: prediction of slow enzyme-inhibitor complex dissociation of a short-living and very long-acting inhibitor. Clin Pharmacokinet. 2013 Feb;52(2):139-51. doi: 10.1007/s40262-012-0024-7. [Article]
    2. Summary of Product Characteristics: Ongentys (opicapone) oral capsules [Link]
    Comments
    Not Available
    Enzymes
    Not Available