Reaction: Codeine to 1 product

Reaction
Codeine
DB00318
Codeine-6-glucuronide
DBMET00660
Reaction type
glucuronidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Cregg R, Russo G, Gubbay A, Branford R, Sato H: Pharmacogenetics of analgesic drugs. Br J Pain. 2013 Nov;7(4):189-208. doi: 10.1177/2049463713507439. [Article]
  2. Codeine FDA label [File]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
UDP-glucuronosyltransferase 2B7Not AvailableNot Availableconfirmed
UDP-glucuronosyltransferase 2B4Not AvailableNot Availableconfirmed