Reaction: Ivermectin to 1 product

Reaction
Ivermectin
DB00602
3''-o-Desmethyl-ivermectin B1b
DBMET03415
Reaction type
O-demethylation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Chiu SH, Sestokas E, Taub R, Smith JL, Arison B, Lu AY: The metabolism of avermectin-H2B1a and -H2B1b by pig liver microsomes. Drug Metab Dispos. 1984 Jul-Aug;12(4):464-9. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 3A4Not AvailableNot Availableimplied