Reaction: Mavacamten to 1 product

Reaction
Mavacamten
DB14921
    MYK-1078
    DBMET03497
    Reaction type
    Aliphatic hydroxylation
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    unknown
    References
    1. Grillo MP, Erve JCL, Dick R, Driscoll JP, Haste N, Markova S, Brun P, Carlson TJ, Evanchik M: In vitro and in vivo pharmacokinetic characterization of mavacamten, a first-in-class small molecule allosteric modulator of beta cardiac myosin. Xenobiotica. 2019 Jun;49(6):718-733. doi: 10.1080/00498254.2018.1495856. Epub 2018 Oct 1. [Article]
    Comments
    Not Available
    Enzymes
    Not Available