Reaction: Imatinib to 2 products

Reaction
Imatinib
DB00619
    Deaminated imatinib
    DBMET03527
    M42.2 imatinib
    DBMET03526
    Reaction type
    Oxidative deamination; carboxylation
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    unknown
    References
    1. Gschwind HP, Pfaar U, Waldmeier F, Zollinger M, Sayer C, Zbinden P, Hayes M, Pokorny R, Seiberling M, Ben-Am M, Peng B, Gross G: Metabolism and disposition of imatinib mesylate in healthy volunteers. Drug Metab Dispos. 2005 Oct;33(10):1503-12. doi: 10.1124/dmd.105.004283. Epub 2005 Jul 8. [Article]
    Comments
    Not Available
    Enzymes
    Not Available