Reaction: Dolutegravir to 1 product

glutathione conjugation; oxidative defluorinationMetabolism of Dolutegravir

Dolutegravir is converted to defluorinated and gutathione conjugated form of dolutegravir (M4.2).

Direction
Activity
active

What you can answer from here — as of October 20, 2022

1ReferenceThe literature this reaction is curated from
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Which metabolites of Dolutegravir are active, and how do they change its interactions?

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