Reaction: 5-fluorouracil to 1 product

5-fluorouracil is converted to dihydrofluorouracil (DHFU) by Dihydropyrimidine dehydrogenase [NADP(+)].

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inactive

What you can answer from here — as of January 19, 2023

1EnzymeEach linked to its target card
Listed above

Which other drugs are metabolised by Dihydropyrimidine dehydrogenase [NADP(+)], and which of those pairings are clinically significant?

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