Reaction: Alprostadil to 1 product
- Reaction
- Reaction type
- oxidation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- inactive
- References
- Hanchanale V, Eardley I: Alprostadil for the treatment of impotence. Expert Opin Pharmacother. 2014 Feb;15(3):421-8. doi: 10.1517/14656566.2014.873789. Epub 2013 Dec 26. [Article]
- Lea AP, Bryson HM, Balfour JA: Intracavernous alprostadil. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in erectile dysfunction. Drugs Aging. 1996 Jan;8(1):56-74. doi: 10.2165/00002512-199608010-00009. [Article]
- Braun, M., Bruch, L., Ney, P., Torsello, G., Schrör, K. (1991). Actions of PGE1, PGE0 and 15-keto-PGE1 on Vessel Tone in Vitro.. In Prostaglandin E1 (pp. 12-20). Springer.
- FDA Approved Drug Products: Edex (alprostadil) injection for intracavernous use only [Link]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Not Available Not Available implied
