Reaction: Umeclidinium to 1 product
- Reaction
- Reaction type
- O-dealkylation
- Direction
- Major circulating metabolite?
- No
- Spontaneous?
- No
- Activity
- inactive
- References
- Gao H, Li J, Chen X, Sun Z, Cui G, Cheng M, Ding L: Pharmacokinetics, metabolite profiling, safety, and tolerability of inhalation aerosol of 101BHG-D01, a novel, long-acting and selective muscarinic receptor antagonist, in healthy Chinese subjects. Front Pharmacol. 2022 Dec 15;13:1064364. doi: 10.3389/fphar.2022.1064364. eCollection 2022. [Article]
- CLINICAL PHARMACOLOGY AND BIOPHARMACEUTICS REVIEW: Umeclidinium Bromide [Link]
- FDA Approved Drug Products: INCRUSE ELLIPTA (umeclidinium inhalation powder) for oral inhalation use [Link]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 2D6 Not Available Not Available implied
