Reaction: [+]-α-HTBZ to 1 product

demethylationMetabolism of Valbenazine

[+]-α-HTBZ is converted to 9-O-desmethyl-dihydrotetrabenazine by Cytochrome P450 2D6.

Reaction
[+]-α-HTBZ
DBMET01448
9-O-desmethyl-dihydrotetrabenazine
DBMET03700
Direction

What you can answer from here — as of August 24, 2023

1EnzymeEach linked to its target card
Listed above

Which other drugs are metabolised by Cytochrome P450 2D6, and which of those pairings are clinically significant?

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