Reaction: Iptacopan to 1 product

Reaction
Iptacopan
DB16200
    M6 iptacopan
    DBMET03749
    Reaction type
    oxidation
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    No
    Activity
    inactive
    References
    1. James AD, Kulmatycki K, Poller B, Romeo AA, Van Lier JJ, Klein K, Pearson D: Absorption, Distribution, Metabolism, and Excretion of [(14)C]iptacopan in Healthy Male Volunteers and in In Vivo and In Vitro Studies. Drug Metab Dispos. 2023 Jul;51(7):873-883. doi: 10.1124/dmd.123.001290. Epub 2023 Jun 12. [Article]
    Comments
    Not Available
    Enzymes
    Not Available