Reaction: Taurolidine to 2 products

Reaction
Taurolidine
DB12473
    Hydroxymethyl taurultam
    DBMET03765
    Taurultam
    DBMET03764
    Reaction type
    hydrolysis
    Direction
    Major circulating metabolite?
    No
    Spontaneous?
    Yes
    Activity
    active
    References
    1. Gong L, Greenberg HE, Perhach JL, Waldman SA, Kraft WK: The pharmacokinetics of taurolidine metabolites in healthy volunteers. J Clin Pharmacol. 2007 Jun;47(6):697-703. doi: 10.1177/0091270007299929. Epub 2007 Mar 29. [Article]
    Comments
    Taurolidine in aqueous solution undergoes rapid conversion to taurultam, with smaller amounts of hydroxymethyltaurultam.
    Enzymes
    Not Available