Reaction: NPC to 1 product

hydrolysisMetabolism of Irinotecan

NPC is converted to SN-38 by Human Carboxylesterases.

Reaction
NPC
DBMET01681
SN-38
DBMET01143
Direction
Activity
active

What you can answer from here — as of March 25, 2024

1EnzymeEach linked to its target card
Listed above

Which other drugs are metabolised by Human Carboxylesterases, and which of those pairings are clinically significant?

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