Reaction: Osimertinib to 1 product
- Reaction
- Reaction type
- demethylation
- Direction
- Major circulating metabolite?
- Yes
- Spontaneous?
- No
- Activity
- active
- References
- FDA Approved Drug Products: TAGRISSO (osimertinib) tablets, for oral use (February 2024) [Link]
- Comments
- Not Available
- Enzymes
Enzyme Km Vmax Role Cytochrome P450 3A Subfamily Not Available Not Available confirmed