| Fluvoxamine | approved, investigational | unknown | enzyme | inhibitor | Details |
| Thiopental | approved, vet_approved | unknown | enzyme | substrate | Details |
| Dolutegravir | approved | no | enzyme | substrate | Details |
| Midostaurin | approved, investigational | unknown | enzyme | substrateinhibitorinducer | Details |
| Rhein | experimental | unknown | enzyme | inhibitor | Details |
| Diacerein | approved, investigational | unknown | target | inhibitor | Details |
| Myrrh | approved | unknown | enzyme | inducer | Details |
| Naldemedine | approved, investigational | no | enzyme | substrate | Details |
| Pibrentasvir | approved, investigational | unknown | enzyme | inhibitor | Details |
| Glecaprevir | approved, investigational | unknown | enzyme | substrateinhibitor | Details |
| Moxisylyte | approved, investigational | no | enzyme | substrate | Details |
| Omega-3-carboxylic acids | approved, investigational | no | enzyme | substrate | Details |
| Lopinavir | approved | no | enzyme | inhibitor | Details |
| Nefazodone | approved, withdrawn | no | enzyme | inhibitor | Details |
| Ambroxol acefyllinate | experimental, investigational | no | enzyme | substrate | Details |
| Mirodenafil | investigational | unknown | enzyme | substrate | Details |
| Elagolix | approved, investigational | no | enzyme | substrate | Details |
| Crizotinib | approved, investigational | unknown | enzyme | substrateinhibitor | Details |
| Acalabrutinib | approved, investigational | unknown | enzyme | substrate | Details |
| Brigatinib | approved, investigational | unknown | enzyme | inducer | Details |
| Foretinib | investigational | unknown | enzyme | substrate | Details |
| Lorlatinib | approved, investigational | unknown | enzyme | substrateinhibitor | Details |
| Phenelzine | approved | unknown | enzyme | inhibitor | Details |
| Ethosuximide | approved | unknown | enzyme | substrate | Details |
| Rifapentine | approved, investigational | unknown | enzyme | inducer | Details |
| Mebendazole | approved, vet_approved | unknown | enzyme | substrate | Details |
| Istradefylline | approved, investigational | unknown | enzyme | inhibitor | Details |
| Olanzapine | approved, investigational | unknown | enzyme | inhibitor | Details |
| Loxoprofen | approved | unknown | enzyme | substrate | Details |
| Prednisone | approved, vet_approved | unknown | enzyme | inducer | Details |
| Budesonide | approved | unknown | enzyme | substrateinducer | Details |
| Methylprednisolone | approved, vet_approved | unknown | enzyme | substrateinducer | Details |
| Lemborexant | approved, investigational | unknown | enzyme | inhibitorinducer | Details |
| Tazemetostat | approved, investigational | unknown | enzyme | substrate | Details |
| Prednisolone phosphate | approved, vet_approved | unknown | enzyme | inducer | Details |
| Tucatinib | approved, investigational | unknown | enzyme | substrate | Details |
| Zanubrutinib | approved, investigational | unknown | enzyme | substrate | Details |
| Selpercatinib | approved, investigational | unknown | enzyme | inhibitor | Details |
| Remoxipride | approved, withdrawn | unknown | enzyme | inhibitor | Details |
| Risdiplam | approved, investigational | unknown | enzyme | inhibitor | Details |
| Lonafarnib | approved, investigational | no | enzyme | substrateinhibitor | Details |
| Relugolix | approved, investigational | unknown | enzyme | substrateinducer | Details |
| Ursodeoxycholic acid | approved, investigational | unknown | enzyme | inducer | Details |
| Ebastine | approved, investigational | unknown | enzyme | substrate | Details |
| Sotorasib | approved, investigational | unknown | enzyme | substrate | Details |
| Quercetin | experimental, investigational | no | enzyme | inhibitor | Details |
| Dextropropoxyphene | approved, illicit, investigational, withdrawn | unknown | enzyme | inhibitor | Details |
| Methadone | approved | no | enzyme | inhibitor | Details |
| Itraconazole | approved, investigational | no | enzyme | inhibitor | Details |
| Birch bark extract | approved, experimental | unknown | enzyme | inhibitor | Details |
| Letermovir | approved, investigational | no | enzyme | substrateinhibitor | Details |