Cefalexin sodiumProduct ingredient for Cephalexin
- Name
- Cefalexin sodium
- Drug Entry
- Cephalexin
Cephalexin is the first of the first generation cephalosporins.7,8 This antibiotic contains a beta lactam and a dihydrothiazide.7 Cephalexin is used to treat a number of susceptible bacterial infections through inhibition of cell wall synthesis.9,Label Cephalexin was approved by the FDA on 4 January 1971.12
- Accession Number
- DBSALT000261
- Structure
Structure for Cefalexin sodium (DBSALT000261)
- Synonyms
- Not Available
- UNII
- F78YJG0WXK
- CAS Number
- 38932-40-0
- Weight
- Average: 369.37
Monoisotopic: 369.07592146 - Chemical Formula
- C16H16N3NaO4S
- InChI Key
- NZDYPHVJLWMLJI-CYJZLJNKSA-M
- InChI
- InChI=1S/C16H17N3O4S.Na/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);/q;+1/p-1/t10-,11-,15-;/m1./s1
- IUPAC Name
- sodium (6R,7R)-7-[(2R)-2-amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- SMILES
- [Na+].[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C([O-])=O
- External Links
- Predicted Properties
Property Value Source Water Solubility 0.386 mg/mL ALOGPS logP 0.51 ALOGPS logP -2.1 Chemaxon logS -3 ALOGPS pKa (Strongest Acidic) 3.26 Chemaxon pKa (Strongest Basic) 7.23 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 115.56 Å2 Chemaxon Rotatable Bond Count 4 Chemaxon Refractivity 99.81 m3·mol-1 Chemaxon Polarizability 34.41 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon