Isoprenaline hydrochlorideProduct ingredient for Isoprenaline

Isoprenaline is a non-selective beta adrenergic receptor agonist indicated to treat heart block, Adams-Stokes attacks, bronchospasm in anesthesia, cadiac arrest, hypovolemic shocks, septic shock, hypoperfusion, congestive hear failure, and cardiogenic shock.^2,14

Isoprenaline research in the 1940s found that this isopropyl analog of epinephrine dilated the bronchi, as well as raising the heart rate and cardiac output, without vasoconstriction.^11,12 The US patent from 1943 states that this compound had a wider therapeutic index and a stronger action than adrenaline.¹⁶

Isoprenaline was granted FDA approval on 19 February 1948.¹³