Mexiletine hydrochlorideProduct ingredient for Mexiletine

Name
Mexiletine hydrochloride
Drug Entry
Mexiletine

Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.

Accession Number
DBSALT000449
Structure
Synonyms
Mexiletine HCl
UNII
606D60IS38
CAS Number
5370-01-4
Weight
Average: 215.72
Monoisotopic: 215.10769191
Chemical Formula
C11H18ClNO
InChI Key
NFEIBWMZVIVJLQ-UHFFFAOYSA-N
InChI
InChI=1S/C11H17NO.ClH/c1-8-5-4-6-9(2)11(8)13-7-10(3)12;/h4-6,10H,7,12H2,1-3H3;1H
IUPAC Name
1-(2,6-dimethylphenoxy)propan-2-amine hydrochloride
SMILES
Cl.CC(N)COC1=C(C)C=CC=C1C
PubChem Compound
21467
ChemSpider
20175
ChEBI
6917
ChEMBL
CHEMBL1200606
Wikipedia
Mexiletine
Predicted Properties
PropertyValueSource
Water Solubility0.538 mg/mLALOGPS
logP2.17ALOGPS
logP2.46Chemaxon
logS-2.5ALOGPS
pKa (Strongest Basic)9.52Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count1Chemaxon
Polar Surface Area35.25 Å2Chemaxon
Rotatable Bond Count3Chemaxon
Refractivity54.97 m3·mol-1Chemaxon
Polarizability21.15 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon