Diethylpropion hydrochlorideProduct ingredient for Diethylpropion

Name
Diethylpropion hydrochloride
Drug Entry
Diethylpropion

A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)

Accession Number
DBSALT000484
Structure
Synonyms
Diethylpropion HCl
UNII
19V2PL39NG
CAS Number
134-80-5
Weight
Average: 241.757
Monoisotopic: 241.123341974
Chemical Formula
C13H20ClNO
InChI Key
ICFXZZFWRWNZMA-UHFFFAOYSA-N
InChI
InChI=1S/C13H19NO.ClH/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12;/h6-11H,4-5H2,1-3H3;1H
IUPAC Name
2-(diethylamino)-1-phenylpropan-1-one hydrochloride
SMILES
Cl.CCN(CC)C(C)C(=O)C1=CC=CC=C1
PubChem Compound
91442
ChemSpider
82571
ChEBI
643703
ChEMBL
CHEMBL1693
Wikipedia
Amfepramone
Predicted Properties
PropertyValueSource
Water Solubility1.22 mg/mLALOGPS
logP2.8ALOGPS
logP2.7Chemaxon
logS-2.2ALOGPS
pKa (Strongest Acidic)17.67Chemaxon
pKa (Strongest Basic)7.44Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count2Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area20.31 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity63.88 m3·mol-1Chemaxon
Polarizability23.96 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon