Diethylpropion hydrochlorideProduct ingredient for Diethylpropion
- Name
- Diethylpropion hydrochloride
- Drug Entry
- Diethylpropion
A appetite depressant considered to produce less central nervous system disturbance than most drugs in this therapeutic category. It is also considered to be among the safest for patients with hypertension. (From AMA Drug Evaluations Annual, 1994, p2290)
- Accession Number
- DBSALT000484
- Structure
- Synonyms
- Diethylpropion HCl
- UNII
- 19V2PL39NG
- CAS Number
- 134-80-5
- Weight
- Average: 241.757
Monoisotopic: 241.123341974 - Chemical Formula
- C13H20ClNO
- InChI Key
- ICFXZZFWRWNZMA-UHFFFAOYSA-N
- InChI
- InChI=1S/C13H19NO.ClH/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12;/h6-11H,4-5H2,1-3H3;1H
- IUPAC Name
- 2-(diethylamino)-1-phenylpropan-1-one hydrochloride
- SMILES
- Cl.CCN(CC)C(C)C(=O)C1=CC=CC=C1
- External Links
- PubChem Compound
- 91442
- ChemSpider
- 82571
- ChEBI
- 643703
- ChEMBL
- CHEMBL1693
- Wikipedia
- Amfepramone
- Predicted Properties
Property Value Source Water Solubility 1.22 mg/mL ALOGPS logP 2.8 ALOGPS logP 2.7 Chemaxon logS -2.2 ALOGPS pKa (Strongest Acidic) 17.67 Chemaxon pKa (Strongest Basic) 7.44 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 20.31 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 63.88 m3·mol-1 Chemaxon Polarizability 23.96 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon