Tolmetin sodiumProduct ingredient for Tolmetin

Name
Tolmetin sodium
Drug Entry
Tolmetin

A non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.

Accession Number
DBSALT000496
Structure
Thumb
Synonyms
Not Available
UNII
WL259637KX
CAS Number
64490-92-2
Weight
Average: 279.2663
Monoisotopic: 279.087137994
Chemical Formula
C15H14NNaO3
InChI Key
QGUALMNFRILWRA-UHFFFAOYSA-M
InChI
InChI=1S/C15H15NO3.Na/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18;/h3-8H,9H2,1-2H3,(H,17,18);/q;+1/p-1
IUPAC Name
sodium 2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetate
SMILES
[Na+].CN1C(CC([O-])=O)=CC=C1C(=O)C1=CC=C(C)C=C1
KEGG Compound
C02328
PubChem Compound
23665411
ChemSpider
43143
ChEBI
9619
ChEMBL
CHEMBL1200613
Wikipedia
Tolmetin
Predicted Properties
PropertyValueSource
Water Solubility0.223 mg/mLALOGPS
logP2.33ALOGPS
logP2.73ChemAxon
logS-3.1ALOGPS
pKa (Strongest Acidic)3.96ChemAxon
pKa (Strongest Basic)-7.8ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area62.13 Å2ChemAxon
Rotatable Bond Count4ChemAxon
Refractivity83.23 m3·mol-1ChemAxon
Polarizability27.26 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon