Flurazepam hydrochlorideProduct ingredient for Flurazepam
- Name
- Flurazepam hydrochloride
- Drug Entry
- Flurazepam
A benzodiazepine derivative used mainly as a hypnotic.
- Accession Number
- DBSALT000543
- Structure
Structure for Flurazepam hydrochloride (DBSALT000543)
- Synonyms
- Flurazepam HCl
- UNII
- 7C4JH842IJ
- CAS Number
- 36105-20-1
- Weight
- Average: 424.339
Monoisotopic: 423.128046024 - Chemical Formula
- C21H24Cl2FN3O
- InChI Key
- PUGVROXLRUQCAF-UHFFFAOYSA-N
- InChI
- InChI=1S/C21H23ClFN3O.ClH/c1-3-25(4-2)11-12-26-19-10-9-15(22)13-17(19)21(24-14-20(26)27)16-7-5-6-8-18(16)23;/h5-10,13H,3-4,11-12,14H2,1-2H3;1H
- IUPAC Name
- 7-chloro-1-[2-(diethylamino)ethyl]-5-(2-fluorophenyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one hydrochloride
- SMILES
- Cl.CCN(CC)CCN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C1=CC=CC=C1F
- External Links
- PubChem Compound
- 37368
- ChemSpider
- 34286
- ChEBI
- 31626
- ChEMBL
- CHEMBL1200602
- Wikipedia
- Flurazepam
- Predicted Properties
Property Value Source Water Solubility 0.01 mg/mL ALOGPS logP 3.81 ALOGPS logP 3.95 Chemaxon logS -4.6 ALOGPS pKa (Strongest Basic) 8.71 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 3 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 35.91 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 107.54 m3·mol-1 Chemaxon Polarizability 41.2 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon