Log in or create an account for full access to this data.
Create a free account or log in to use this tool.
Create a free account or log in to explore DrugBank data.
Flurazepam is a long-acting benzodiazepine with a rapid onset of action that is commonly used to treat insomnia. A benzodiazepine derivative used mainly as a hypnotic.
- Mechanism
- Curator reviewed
Flurazepam binds to an allosteric site on GABA-A receptors. Binding potentiates the action of GABA on GABA-A receptors by opening the chloride channel within the receptor, causing chloride influx and hyperpolarization.
- Primary indication
- For short-term and intermittent use in patients with recurring insomnia and poor sleeping habitsCurator reviewed · 1 structured indication
- Formula / weight
- C21H23ClFN3O · 387.878 g/mol (avg)
- First approval
- Canada, 1997 · United States, 1985
- Code names
- ID 480 · Ro 5-6901
- Brand names
- Dalmane
Resolves to
Clinical / RWD
Structure
InChIKey
SAADBVWGJQAEFS-UHFFFAOYSA-NSMILESCCN(CC)CCN1C2=C(C=C(Cl)C=C2)C(=NCC1=O)C1=CC=CC=C1FTargets
Transporters
What you can answer from here — as of September 23, 2026
3Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
2TransportersSubstrate / inhibitor direction, not just membership
Listed above
Which drugs share a target with Flurazepam, and which of those have an active Phase 3 trial?