Hydralazine hydrochlorideProduct ingredient for Hydralazine

Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed.¹⁵ Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.^10,19,20 Hydralazine is no longer a first line therapy for these indications since the development of newer antihypertensive medications.¹⁷

Hydralazine hydrochloride was FDA approved on 15 January 1953.¹⁸