Fencamfamine hydrochlorideProduct ingredient for Fencamfamin
- Name
- Fencamfamine hydrochloride
- Drug Entry
- Fencamfamin
Fencamfamin (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant, but was later withdrawn for this application due to problems with dependence and abuse. It is around half the potency of dexamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose. Fencamfamin is used for treating depressive day-time fatigue, lack of concentration and lethargy. It is especially useful in patients with chronic conditions due to its favourable safety profile.
- Accession Number
- DBSALT000814
- Structure
- Synonyms
- Fencamfamine HCl
- UNII
- 0M1J60BWEX
- CAS Number
- 2240-14-4
- Weight
- Average: 251.795
Monoisotopic: 251.144077416 - Chemical Formula
- C15H22ClN
- InChI Key
- CVFSMSTXULJISA-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H21N.ClH/c1-2-16-15-13-9-8-12(10-13)14(15)11-6-4-3-5-7-11;/h3-7,12-16H,2,8-10H2,1H3;1H
- IUPAC Name
- N-ethyl-3-phenylbicyclo[2.2.1]heptan-2-amine hydrochloride
- SMILES
- Cl.CCNC1C2CCC(C2)C1C1=CC=CC=C1
- External Links
- PubChem Compound
- 102773
- ChemSpider
- 92834
- ChEMBL
- CHEMBL2106270
- Predicted Properties
Property Value Source Water Solubility 0.00295 mg/mL ALOGPS logP 3.46 ALOGPS logP 3.21 Chemaxon logS -4.9 ALOGPS pKa (Strongest Basic) 10.56 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 12.03 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 67.64 m3·mol-1 Chemaxon Polarizability 26.13 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon