Bupranolol hydrochlorideProduct ingredient for Bupranolol

Show full entry for Bupranolol
Name
Bupranolol hydrochloride
Drug Entry
Bupranolol

Bupranolol is a non-selective beta blocker with potency similar to propanolol. It does not have intrinsic sympathomimetic activity (ISA), but does have strong membrane stabilizing activity.

See full entry for Bupranolol
Accession Number
DBSALT000905
Structure
Similar Structures
Synonyms
Bupranolol HCl
External IDs
B 1312 / B-1312 / KL 255 / KL-255
UNII
DTC2G3GDPL
CAS Number
15148-80-8
Weight
Average: 308.24
Monoisotopic: 307.1105844
Chemical Formula
C14H23Cl2NO2
InChI Key
WJUUZHQWGKSLIJ-UHFFFAOYSA-N
InChI
InChI=1S/C14H22ClNO2.ClH/c1-10-5-6-12(15)13(7-10)18-9-11(17)8-16-14(2,3)4;/h5-7,11,16-17H,8-9H2,1-4H3;1H
IUPAC Name
1-(tert-butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol hydrochloride
SMILES
Cl.CC1=CC(OCC(O)CNC(C)(C)C)=C(Cl)C=C1
PubChem Compound
27072
ChemSpider
25195
ChEBI
31323
Predicted Properties
PropertyValueSource
Water Solubility0.143 mg/mLALOGPS
logP3.14ALOGPS
logP2.99Chemaxon
logS-3.3ALOGPS
pKa (Strongest Acidic)14.09Chemaxon
pKa (Strongest Basic)9.76Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area41.49 Å2Chemaxon
Rotatable Bond Count6Chemaxon
Refractivity74.86 m3·mol-1Chemaxon
Polarizability30.19 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon