Dimetindene maleateProduct ingredient for Dimetindene
- Name
- Dimetindene maleate
- Drug Entry
- Dimetindene
Dimetindene (Fenistil) is an antihistamine/anticholinergic used orally and locally as an antipruritic.
- Accession Number
- DBSALT000908
- Structure
Structure for Dimetindene maleate (DBSALT000908)
- Synonyms
- Not Available
- UNII
- 6LL60J9E0O
- CAS Number
- 3614-69-5
- Weight
- Average: 408.498
Monoisotopic: 408.20490739 - Chemical Formula
- C24H28N2O4
- InChI Key
- SWECWXGUJQLXJF-BTJKTKAUSA-N
- InChI
- InChI=1S/C20H24N2.C4H4O4/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20;5-3(6)1-2-4(7)8/h4-10,12,15H,11,13-14H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
- IUPAC Name
- (2Z)-but-2-enedioic acid; dimethyl(2-{3-[1-(pyridin-2-yl)ethyl]-1H-inden-2-yl}ethyl)amine
- SMILES
- OC(=O)\C=C/C(O)=O.CC(C1=C(CCN(C)C)CC2=C1C=CC=C2)C1=CC=CC=N1
- External Links
- PubChem Compound
- 5282414
- ChemSpider
- 4445569
- ChEBI
- 31500
- ChEMBL
- CHEMBL1870768
- Predicted Properties
Property Value Source Water Solubility 0.0384 mg/mL ALOGPS logP 4.03 ALOGPS logP 3.74 Chemaxon logS -3.9 ALOGPS pKa (Strongest Acidic) 18.93 Chemaxon pKa (Strongest Basic) 9.7 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 16.13 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 93.57 m3·mol-1 Chemaxon Polarizability 35.08 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon