Pemirolast potassiumProduct ingredient for Pemirolast
- Name
- Pemirolast potassium
- Drug Entry
- Pemirolast
Pemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis. Pemirolast is potentially useful for prophylaxis of pulmonary hypersensitivity reactions to drugs such as paclitaxel.
- Accession Number
- DBSALT000925
- Structure
Structure for Pemirolast potassium (DBSALT000925)
- Synonyms
- Not Available
- UNII
- 497A17OUUE
- CAS Number
- 100299-08-9
- Weight
- Average: 266.305
Monoisotopic: 266.03184036 - Chemical Formula
- C10H7KN6O
- InChI Key
- NMMVKSMGBDRONO-UHFFFAOYSA-N
- InChI
- InChI=1S/C10H7N6O.K/c1-6-3-2-4-16-9(6)11-5-7(10(16)17)8-12-14-15-13-8;/h2-5H,1H3;/q-1;+1
- IUPAC Name
- potassium 5-{9-methyl-4-oxo-4H-pyrido[1,2-a]pyrimidin-3-yl}-1H-1,2,3,4-tetrazol-1-ide
- SMILES
- [K+].CC1=CC=CN2C(=O)C(=CN=C12)C1=NN=N[N-]1
- External Links
- PubChem Compound
- 443866
- ChemSpider
- 51989
- BindingDB
- 50248065
- ChEBI
- 775001
- ChEMBL
- CHEMBL1201050
- Predicted Properties
Property Value Source Water Solubility 5.02 mg/mL ALOGPS logP 0.26 ALOGPS logP 0.24 Chemaxon logS -1.7 ALOGPS pKa (Strongest Acidic) 2.6 Chemaxon pKa (Strongest Basic) -1.1 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 84.23 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 64.09 m3·mol-1 Chemaxon Polarizability 21.48 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon