Pemirolast is a medication used to treat allergies such as hay fever and allergic conjunctivitis. Pemirolast potassium is a slightly yellow powder that is soluble in water.
- Mechanism
- Curator reviewed
Pemirolast binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. Pemirolast has also been observed to inhibit antigen-stimulated calcium ion influx into mast cells through the blockage of calcium channels. Pemirolast inhibits the chemotaxis of eosinophils into ocular tissue, and prevents inflammatory mediator release from human eosinophils.
- Primary indication
- For the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitisCurator reviewed · 2 structured indications
- Formula / weight
- C10H8N6O · 228.2101 g/mol (avg)
- First approval
- United States, 2000
- Code names
- BMY 26517 · CRD007 · DE 068 · TBX
Resolves to
HIANJWSAHKJQTH-UHFFFAOYSA-NSMILESCC1=CC=CN2C(=O)C(=CN=C12)C1=NNN=N1What you can answer from here — as of September 13, 2026
Which drugs share a target with Pemirolast, and which of those have an active Phase 3 trial?
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