Viomycin sulfateProduct ingredient for Viomycin
- Name
- Viomycin sulfate
- Drug Entry
- Viomycin
Viomycin is a tuberactinomycin antibiotic that was used to treat Mycobacterium tuberculosis until it was replaced by the less toxic capreomycin. These drugs bind RNA in bacterial ribosomes and inhibit protein synthesis. Viomycin was derived from the actinomycete Streptomyces puniceus.
- Accession Number
- DBSALT000952
- Structure
Structure for Viomycin sulfate (DBSALT000952)
- Synonyms
- Viomycin sulfate
- UNII
- LKO141R05V
- CAS Number
- 37883-00-4
- Weight
- Average: 783.77
Monoisotopic: 783.292964355 - Chemical Formula
- C25H45N13O14S
- InChI Key
- AQONYROJHRNYQQ-QMAPKBLTSA-N
- InChI
- InChI=1S/C25H43N13O10.H2O4S/c26-3-1-2-10(27)4-16(41)32-12-6-30-23(47)18(11-5-17(42)37-24(28)36-11)38-20(44)13(7-31-25(29)48)33-21(45)14(8-39)35-22(46)15(9-40)34-19(12)43;1-5(2,3)4/h7,10-12,14-15,17-18,39-40,42H,1-6,8-9,26-27H2,(H,30,47)(H,32,41)(H,33,45)(H,34,43)(H,35,46)(H,38,44)(H3,28,36,37)(H3,29,31,48);(H2,1,2,3,4)/b13-7-;/t10-,11+,12-,14-,15-,17-,18-;/m0./s1
- IUPAC Name
- (3S)-3,6-diamino-N-[(3S,6Z,9S,12S,15S)-6-[(carbamoylamino)methylidene]-3-[(4R,6S)-6-hydroxy-2-imino-1,3-diazinan-4-yl]-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentaazacyclohexadecan-15-yl]hexanamide; sulfuric acid
- SMILES
- OS(O)(=O)=O.[H][C@@]1(C[C@H](O)NC(=N)N1)[C@]1([H])NC(=O)\C(NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CNC1=O)NC(=O)C[C@@H](N)CCCN)=C\NC(N)=O
- External Links
- ChemSpider
- 4445631
- ChEMBL
- CHEMBL3989823
- Wikipedia
- Viomycin
- Predicted Properties
Property Value Source Water Solubility 1.04 mg/mL ALOGPS logP -3.4 ALOGPS logP -11 Chemaxon logS -2.8 ALOGPS pKa (Strongest Acidic) 8.89 Chemaxon pKa (Strongest Basic) 10.42 Chemaxon Physiological Charge 3 Chemaxon Hydrogen Acceptor Count 15 Chemaxon Hydrogen Donor Count 16 Chemaxon Polar Surface Area 390.36 Å2 Chemaxon Rotatable Bond Count 10 Chemaxon Refractivity 171.46 m3·mol-1 Chemaxon Polarizability 66.95 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon