Prilocaine hydrochlorideProduct ingredient for Prilocaine

Show full entry for Prilocaine
Name
Prilocaine hydrochloride
Drug Entry
Prilocaine

A local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)

See full entry for Prilocaine
Accession Number
DBSALT000962
Structure
Similar Structures
Synonyms
Prilocaine HCl
UNII
MJW015BAPH
CAS Number
1786-81-8
Weight
Average: 256.77
Monoisotopic: 256.134241
Chemical Formula
C13H21ClN2O
InChI Key
BJPJNTKRKALCPP-UHFFFAOYSA-N
InChI
InChI=1S/C13H20N2O.ClH/c1-4-9-14-11(3)13(16)15-12-8-6-5-7-10(12)2;/h5-8,11,14H,4,9H2,1-3H3,(H,15,16);1H
IUPAC Name
N-(2-methylphenyl)-2-(propylamino)propanimidic acid hydrochloride
SMILES
Cl.CCCNC(C)C(O)=NC1=CC=CC=C1C
ChemSpider
83207
ChEBI
32053
ChEMBL
CHEMBL1200586
Wikipedia
Prilocaine
Predicted Properties
PropertyValueSource
Water Solubility0.355 mg/mLALOGPS
logP1.85ALOGPS
logP0.95Chemaxon
logS-2.8ALOGPS
pKa (Strongest Acidic)3.52Chemaxon
pKa (Strongest Basic)9.05Chemaxon
Physiological Charge1Chemaxon
Hydrogen Acceptor Count3Chemaxon
Hydrogen Donor Count2Chemaxon
Polar Surface Area44.62 Å2Chemaxon
Rotatable Bond Count5Chemaxon
Refractivity68.62 m3·mol-1Chemaxon
Polarizability26.21 Å3Chemaxon
Number of Rings1Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterYesChemaxon
Veber's RuleNoChemaxon
MDDR-like RuleNoChemaxon