Trimipramine maleateProduct ingredient for Trimipramine

Name
Trimipramine maleate
Drug Entry
Trimipramine

Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.

Accession Number
DBSALT000969
Structure
Synonyms
Not Available
UNII
269K6498LD
CAS Number
521-78-8
Weight
Average: 410.514
Monoisotopic: 410.220557454
Chemical Formula
C24H30N2O4
InChI Key
YDGHCKHAXOUQOS-BTJKTKAUSA-N
InChI
InChI=1S/C20H26N2.C4H4O4/c1-16(14-21(2)3)15-22-19-10-6-4-8-17(19)12-13-18-9-5-7-11-20(18)22;5-3(6)1-2-4(7)8/h4-11,16H,12-15H2,1-3H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
IUPAC Name
(2Z)-but-2-enedioic acid; (3-{2-azatricyclo[9.4.0.0³,⁸]pentadeca-1(15),3,5,7,11,13-hexaen-2-yl}-2-methylpropyl)dimethylamine
SMILES
[H]\C(=C(/[H])C(O)=O)C(O)=O.CC(CN(C)C)CN1C2=CC=CC=C2CCC2=CC=CC=C12
KEGG Compound
C14029
ChemSpider
4445487
ChEBI
35030
ChEMBL
CHEMBL1200948
Wikipedia
Trimipramine
Predicted Properties
PropertyValueSource
Water Solubility0.026 mg/mLALOGPS
logP4.67ALOGPS
logP4.76ChemAxon
logS-4ALOGPS
pKa (Strongest Basic)9.42ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area6.48 Å2ChemAxon
Rotatable Bond Count6ChemAxon
Refractivity95.02 m3·mol-1ChemAxon
Polarizability35.32 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon