Cloperastine hydrochlorideProduct ingredient for Cloperastine

Name
Cloperastine hydrochloride
Drug Entry
Cloperastine

Cloperastine is a cough suppressant that acts on the central nervous system.

Accession Number
DBSALT001087
Structure
Thumb
Synonyms
Cloperastine HCl
UNII
PI4N7C63ND
CAS Number
14984-68-0
Weight
Average: 366.33
Monoisotopic: 365.1313198
Chemical Formula
C20H25Cl2NO
InChI Key
UNPLRYRWJLTVAE-UHFFFAOYSA-N
InChI
InChI=1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H
IUPAC Name
1-{2-[(4-chlorophenyl)(phenyl)methoxy]ethyl}piperidine hydrochloride
SMILES
Cl.ClC1=CC=C(C=C1)C(OCCN1CCCCC1)C1=CC=CC=C1
ChemSpider
141526
ChEBI
31420
ChEMBL
CHEMBL1492516
Predicted Properties
PropertyValueSource
Water Solubility0.000765 mg/mLALOGPS
logP5.08ALOGPS
logP5.11ChemAxon
logS-5.6ALOGPS
pKa (Strongest Basic)8.82ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area12.47 Å2ChemAxon
Rotatable Bond Count6ChemAxon
Refractivity96.87 m3·mol-1ChemAxon
Polarizability37.23 Å3ChemAxon
Number of Rings3ChemAxon
Bioavailability1ChemAxon
Rule of FiveNoChemAxon
Ghose FilterYesChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleYesChemAxon