Cloperastine hydrochlorideProduct ingredient for Cloperastine
- Name
- Cloperastine hydrochloride
- Drug Entry
- Cloperastine
Cloperastine is a cough suppressant that acts on the central nervous system.
- Accession Number
- DBSALT001087
- Structure
Structure for Cloperastine hydrochloride (DBSALT001087)
- Synonyms
- Cloperastine HCl
- UNII
- PI4N7C63ND
- CAS Number
- 14984-68-0
- Weight
- Average: 366.33
Monoisotopic: 365.1313198 - Chemical Formula
- C20H25Cl2NO
- InChI Key
- UNPLRYRWJLTVAE-UHFFFAOYSA-N
- InChI
- InChI=1S/C20H24ClNO.ClH/c21-19-11-9-18(10-12-19)20(17-7-3-1-4-8-17)23-16-15-22-13-5-2-6-14-22;/h1,3-4,7-12,20H,2,5-6,13-16H2;1H
- IUPAC Name
- 1-{2-[(4-chlorophenyl)(phenyl)methoxy]ethyl}piperidine hydrochloride
- SMILES
- Cl.ClC1=CC=C(C=C1)C(OCCN1CCCCC1)C1=CC=CC=C1
- External Links
- ChemSpider
- 141526
- ChEBI
- 31420
- ChEMBL
- CHEMBL1492516
- Predicted Properties
Property Value Source Water Solubility 0.000765 mg/mL ALOGPS logP 5.08 ALOGPS logP 5.11 Chemaxon logS -5.6 ALOGPS pKa (Strongest Basic) 8.82 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 12.47 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 96.87 m3·mol-1 Chemaxon Polarizability 37.23 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon