Dimetacrine bitartrateProduct ingredient for Dimetacrine
- Name
- Dimetacrine bitartrate
- Drug Entry
- Dimetacrine
Dimetacrine is also known as dimethacrine or acripamine. It is marketed under the names Istonil, Istonyl, Linostil, and Miroistonil. Dimetacrine is a tricyclic antidepressant (TCA) with imipramine-like effects used in Europe for the treatment of depression. Dimetacrine is no longer used in Japan.
- Accession Number
- DBSALT001096
- Structure
Structure for Dimetacrine bitartrate (DBSALT001096)
- Synonyms
- Not Available
- UNII
- DVH164X0IF
- CAS Number
- 3759-07-7
- Weight
- Average: 444.528
Monoisotopic: 444.226036758 - Chemical Formula
- C24H32N2O6
- InChI Key
- IIYKUJVECNNTEY-LREBCSMRSA-N
- InChI
- InChI=1S/C20H26N2.C4H6O6/c1-20(2)16-10-5-7-12-18(16)22(15-9-14-21(3)4)19-13-8-6-11-17(19)20;5-1(3(7)8)2(6)4(9)10/h5-8,10-13H,9,14-15H2,1-4H3;1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1
- IUPAC Name
- (2R,3R)-2,3-dihydroxybutanedioic acid; [3-(9,9-dimethyl-9,10-dihydroacridin-10-yl)propyl]dimethylamine
- SMILES
- O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN(C)CCCN1C2=CC=CC=C2C(C)(C)C2=C1C=CC=C2
- External Links
- Predicted Properties
Property Value Source Water Solubility 0.0343 mg/mL ALOGPS logP 4.96 ALOGPS logP 4.42 Chemaxon logS -3.9 ALOGPS pKa (Strongest Basic) 9.2 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 6.48 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 105.52 m3·mol-1 Chemaxon Polarizability 35.6 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon