Ceftriaxone sodiumProduct ingredient for Ceftriaxone

Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic.¹ It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges¹, eyes⁹, and inner ear⁶. Ceftriaxone has broader and stronger gram-negative coverage then first or second-generation cephalosporins, but worse activity against methicillin-susceptible S.aureus. Ceftriaxone is a commonly used antimicrobial due to its good activity against multi-drug resistant Enterobacteriaceae, its relatively safe adverse effect profile, and its long half-life which allows for the convenience of daily or twice-daily dosing.¹