Sulbactam sodiumProduct ingredient for Sulbactam
- Name
- Sulbactam sodium
- Drug Entry
- Sulbactam
Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus.6 When given in combination with β-lactam antibiotics, sulbactam produces a synergistic effect as it blocks the enzyme responsible for drug resistance by hydrolyzing β-lactams.2
- Accession Number
- DBSALT001310
- Structure
- Synonyms
- Not Available
- External IDs
- CP 458992 / CP-45899-2 / CP-458992 / CP458992
- UNII
- DKQ4T82YE6
- CAS Number
- 69388-84-7
- Weight
- Average: 255.22
Monoisotopic: 255.01773788 - Chemical Formula
- C8H10NNaO5S
- InChI Key
- NKZMPZCWBSWAOX-IBTYICNHSA-M
- InChI
- InChI=1S/C8H11NO5S.Na/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14;/h5-6H,3H2,1-2H3,(H,11,12);/q;+1/p-1/t5-,6+;/m1./s1
- IUPAC Name
- sodium (2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
- SMILES
- [Na+].CC1(C)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C([O-])=O
- External Links
- KEGG Compound
- C14001
- ChemSpider
- 571120
- ChEBI
- 157785
- ChEMBL
- CHEMBL1200944
- Wikipedia
- Sulbactam
- Predicted Properties
Property Value Source Water Solubility 33.8 mg/mL ALOGPS logP -0.1 ALOGPS logP -0.89 Chemaxon logS -0.88 ALOGPS pKa (Strongest Acidic) 3.09 Chemaxon pKa (Strongest Basic) -3.8 Chemaxon Physiological Charge -1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 94.58 Å2 Chemaxon Rotatable Bond Count 1 Chemaxon Refractivity 59.05 m3·mol-1 Chemaxon Polarizability 20.19 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon