Sulbactam

DB09324ApprovedInvestigationalSmall moleculebeta-Lactamase Inhibitors

Sulbactam is an beta-lactamase inhibitor antibiotic combined with other antibiotics to treat a variety of susceptible bacterial infections. Sulbactam is a beta (β)-lactamase inhibitor and a derivative of the basic penicillin nucleus.

Chemical structure of Sulbactam
Mechanism
Curator reviewed · 2 references
Primary indication
Sulbactam is used in combination with other antibacterial agents.Curator reviewed · 20 structured indications
Formula / weight
C8H11NO5S · 233.242 g/mol (avg)
First approval
United States, 1991
Code names
CP-45899
Brand names
  • Unasyn
  • Xacduro

Resolves to

Compound
UNIIS4TF6I2330CAS68373-14-8ChEMBLCHEMBL403ChEBI9321PubChem130313KEGGD02223
Clinical / RWD
RxNorm10167ATCJ01CG01
Structure
InChIKeyFKENQMMABCRJMK-RITPCOANSA-NSMILES[H][C@@]12CC(=O)N1[C@@]([H])(C(O)=O)C(C)(C)S2(=O)=O
Targets
P00807blaZP62593bla
Transporters
Q4U2R8SLC22A6

What you can answer from here — as of September 23, 2026

2Protein targetsEach mapped to UniProt, with action and pharmacological action
Listed above
1TransporterSubstrate / inhibitor direction, not just membership
Listed above
774Drug interactionsStructured to mechanism, not free text
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63Clinical trialsPhase, status and sponsor resolved per trial
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20Structured indicationsCondition, population, route and combination as fields, not prose
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1ContraindicationEach with its own population and attribute set
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331Marketed productsAcross 9 countries and 104 labellers
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1ATC codeIncluding every combination product, plus 13 drug categories
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13+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Sulbactam, and which of those have an active Phase 3 trial?

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