Sulconazole nitrateProduct ingredient for Sulconazole
- Name
- Sulconazole nitrate
- Drug Entry
- Sulconazole
Sulconazole, brand name Exelderm, is a broad-spectrum anti-fungal agent available as a topical cream and solution. Sulconazole nitrate, the active ingredient, is an imidazole derivative that inhibits the growth of common pathogenic dermatophytes, making it an effective treatment for tinea cruris and tinea corporis infections.6,7 Sulconazole appears to be effective and well-tolerated in the treatment of superficial fungal infections.4
- Accession Number
- DBSALT001375
- Structure
Structure for Sulconazole nitrate (DBSALT001375)
- Synonyms
- Not Available
- UNII
- 1T89100D5U
- CAS Number
- 61318-91-0
- Weight
- Average: 460.75
Monoisotopic: 458.9977957 - Chemical Formula
- C18H16Cl3N3O3S
- InChI Key
- CRKGMGQUHDNAPB-UHFFFAOYSA-N
- InChI
- InChI=1S/C18H15Cl3N2S.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)
- IUPAC Name
- 1-(2-{[(4-chlorophenyl)methyl]sulfanyl}-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole; nitric acid
- SMILES
- ON(=O)=O.ClC1=CC=C(CSC(CN2C=CN=C2)C2=C(Cl)C=C(Cl)C=C2)C=C1
- External Links
- ChemSpider
- 58943
- ChEBI
- 9326
- ChEMBL
- CHEMBL1200348
- Wikipedia
- Sulconazole
- Predicted Properties
Property Value Source Water Solubility 0.00129 mg/mL ALOGPS logP 5.72 ALOGPS logP 6.06 Chemaxon logS -5.5 ALOGPS pKa (Strongest Basic) 6.78 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 1 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 17.82 Å2 Chemaxon Rotatable Bond Count 6 Chemaxon Refractivity 104.37 m3·mol-1 Chemaxon Polarizability 39.96 Å3 Chemaxon Number of Rings 3 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon