Chlophedianol hydrochlorideProduct ingredient for Clofedanol
- Name
- Chlophedianol hydrochloride
- Drug Entry
- Clofedanol
Clofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
- Accession Number
- DBSALT001414
- Structure
- Synonyms
- Chlophedianol HCl
- UNII
- 69QQ58998Y
- CAS Number
- 511-13-7
- Weight
- Average: 326.26
Monoisotopic: 325.1000197 - Chemical Formula
- C17H21Cl2NO
- InChI Key
- XYGSFNHCFFAJPO-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H20ClNO.ClH/c1-19(2)13-12-17(20,14-8-4-3-5-9-14)15-10-6-7-11-16(15)18;/h3-11,20H,12-13H2,1-2H3;1H
- IUPAC Name
- 1-(2-chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol hydrochloride
- SMILES
- Cl.CN(C)CCC(O)(C1=CC=CC=C1)C1=CC=CC=C1Cl
- External Links
- ChemSpider
- 75633
- ChEBI
- 31392
- ChEMBL
- CHEMBL1200972
- Wikipedia
- Clofedanol
- Predicted Properties
Property Value Source Water Solubility 0.0621 mg/mL ALOGPS logP 3.51 ALOGPS logP 3.46 Chemaxon logS -3.7 ALOGPS pKa (Strongest Acidic) 13.18 Chemaxon pKa (Strongest Basic) 8.87 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 23.47 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 84.94 m3·mol-1 Chemaxon Polarizability 31.65 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon