Acetophenazine maleateProduct ingredient for Acetophenazine
- Name
- Acetophenazine maleate
- Drug Entry
- Acetophenazine
Acetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. It is also used to help treat false perceptions (e.g. hallucinations or delusions). It primarily targets the dopamine D2 receptor.
- Accession Number
- DBSALT001415
- Structure
Structure for Acetophenazine maleate (DBSALT001415)
- Synonyms
- Not Available
- UNII
- 3P5HNU5JTC
- CAS Number
- 5714-00-1
- Weight
- Average: 643.71
Monoisotopic: 643.219965577 - Chemical Formula
- C31H37N3O10S
- InChI Key
- NUKVZKPNSKJGBK-SPIKMXEPSA-N
- InChI
- InChI=1S/C23H29N3O2S.2C4H4O4/c1-18(28)19-7-8-23-21(17-19)26(20-5-2-3-6-22(20)29-23)10-4-9-24-11-13-25(14-12-24)15-16-27;2*5-3(6)1-2-4(7)8/h2-3,5-8,17,27H,4,9-16H2,1H3;2*1-2H,(H,5,6)(H,7,8)/b;2*2-1-
- IUPAC Name
- bis((2Z)-but-2-enedioic acid); 1-(10-{3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl}-10H-phenothiazin-2-yl)ethan-1-one
- SMILES
- [H]\C(=C(/[H])C(O)=O)C(O)=O.[H]\C(=C(/[H])C(O)=O)C(O)=O.CC(=O)C1=CC2=C(SC3=CC=CC=C3N2CCCN2CCN(CCO)CC2)C=C1
- External Links
- ChemSpider
- 4444538
- ChEBI
- 2402
- ChEMBL
- CHEMBL2360079
- Wikipedia
- Acetophenazine
- Predicted Properties
Property Value Source Water Solubility 0.0601 mg/mL ALOGPS logP 3.48 ALOGPS logP 2.65 Chemaxon logS -3.8 ALOGPS pKa (Strongest Acidic) 15.46 Chemaxon pKa (Strongest Basic) 8.07 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 5 Chemaxon Hydrogen Donor Count 1 Chemaxon Polar Surface Area 47.02 Å2 Chemaxon Rotatable Bond Count 11 Chemaxon Refractivity 121.7 m3·mol-1 Chemaxon Polarizability 46.83 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 0 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule Yes Chemaxon