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Acetophenazine is an antipsychotic drug of moderate-potency. It is used in the treatment of disorganized and psychotic thinking. It is also used to help treat false perceptions (e.g. hallucinations or... It primarily targets the dopamine D2 receptor.
- Mechanism
- Curator reviewed
Acetophenazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.
- Primary indication
- For the treatment of disorganized and psychotic thinking.Curator reviewed
- Formula / weight
- C23H29N3O2S · 411.56 g/mol (avg)
Resolves to
WNTYBHLDCKXEOT-UHFFFAOYSA-NSMILESCC(=O)C1=CC=C2SC3=C(C=CC=C3)N(CCCN3CCN(CCO)CC3)C2=C1What you can answer from here — as of September 13, 2026
Which drugs share a target with Acetophenazine, and which of those have an active Phase 3 trial?