Risedronate sodium hemi-pentahydrateProduct ingredient for Risedronic acid
- Name
- Risedronate sodium hemi-pentahydrate
- Drug Entry
- Risedronic acid
Risedronic acid is a third generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's diseaseLabel1,2. It functions by preventing resorption of boneLabel1.
- Accession Number
- DBSALT001515
- Structure
Structure for Risedronate sodium hemi-pentahydrate (DBSALT001515)
- Synonyms
- Risedronate sodium 2.5-hydrate / Risedronate sodium hemi-pentahydrate / Risedronate sodium hemipentahydrate / Risedronic acid monosodium salt hemipentahydrate / Sodium risedronate hydrate
- UNII
- HU2YAQ274O
- CAS Number
- 329003-65-8
- Weight
- Average: 700.264
Monoisotopic: 700.01886331 - Chemical Formula
- C14H30N2Na2O19P4
- InChI Key
- HYFDYHPNTXOPPO-UHFFFAOYSA-L
- InChI
- InChI=1S/2C7H11NO7P2.2Na.5H2O/c2*9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6;;;;;;;/h2*1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15);;;5*1H2/q;;2*+1;;;;;/p-2
- IUPAC Name
- disodium pentahydrate bis(hydrogen [1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonate)
- SMILES
- O.O.O.O.O.[Na+].[Na+].OC(CC1=CN=CC=C1)(P(O)(O)=O)P(O)([O-])=O.OC(CC1=CN=CC=C1)(P(O)(O)=O)P(O)([O-])=O
- External Links
- ChemSpider
- 10128617
- Predicted Properties
Property Value Source Water Solubility 16.5 mg/mL ALOGPS logP -0.59 ALOGPS logP -3.3 Chemaxon logS -1.3 ALOGPS pKa (Strongest Acidic) 0.68 Chemaxon pKa (Strongest Basic) 4.91 Chemaxon Physiological Charge -3 Chemaxon Hydrogen Acceptor Count 8 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 151.01 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 56 m3·mol-1 Chemaxon Polarizability 21.53 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon